Article
miR-146a G>C polymorphisms and risk of hepatocellular carcinoma in a Chinese population.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jun 2014
Cong Ning, Chen Hua, Bu Wen-Zhe, Li Jin-Peng, Liu Ning, Song Jin-Long
Abstract excerpt
MicroRNAs (miRNAs) are thought to have a role in cancer development. We investigated the association among miR-146a G>C genetic variations, hepatitis B (HBV), and C (HCV) infection, and risk of hepatocellular carcinoma (HCC). Unconditional logistical regression analysis suggested that the miR-146a GG genotype and G allele carried a 2.10- (95 % confidence interval (CI)=1.03-4.37) and 1.42-fold (95 % CI=1.07-1.92)...
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