Article
Association of the microRNA-499 variants with susceptibility to hepatocellular carcinoma in a Chinese population.
Molecular biology reports - 1 Jun 2012
Xiang Yu, Fan Song, Cao Ju, Huang Shifeng, Zhang Li-ping
Abstract excerpt
microRNAs (miRNAs) are a new class of small non-coding RNAs that function as tumor suppressors or oncogenes. Single nucleotide polymorphisms (SNPs) in miRNA may contribute to cancer development. We hypothesized that genetic variations of the miRNA could be associated with the risk of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). A total of 100 patients with HCC, 100 cases of chronic hepatitis B...
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