Association of the microRNA-499 variants with susceptibility to hepatocellular carcinoma in a Chinese population.

doi:10.1007/s11033-012-1532-0

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Article

Association of the microRNA-499 variants with susceptibility to hepatocellular carcinoma in a Chinese population.

Molecular biology reports - 1 Jun 2012

Xiang Yu, Fan Song, Cao Ju, Huang Shifeng, Zhang Li-ping

Abstract excerpt

microRNAs (miRNAs) are a new class of small non-coding RNAs that function as tumor suppressors or oncogenes. Single nucleotide polymorphisms (SNPs) in miRNA may contribute to cancer development. We hypothesized that genetic variations of the miRNA could be associated with the risk of hepatitis B...

Topics

Adult
Amplified Fragment Length Polymorphism Analysis
Asian People
Carcinoma, Hepatocellular
Case-Control Studies
Female
Gene Frequency
Genetic Association Studies
Genetic Predisposition to Disease
Hepatitis B, Chronic
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Liver Neoplasms

Male

MicroRNAs

Middle Aged

Odds Ratio

Polymorphism, Single Nucleotide

Risk Factors

Source

Open in PubMed

Identifiers

PMID: 22311030
DOI: 10.1007/s11033-012-1532-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-22311030-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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