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Article

Myocardial infarction in a 36-year-old man with combined ABCA1 and APOA-1 deficiency.

Journal of clinical lipidology - 1 Jan 2000

van Capelleveen Julian C, Kootte Ruud S, Hovingh G Kees, Bochem Andrea E

Abstract excerpt

In this report, we present a patient who suffered from a myocardial infarction at an extremely young age. The only remarkable finding in the risk factor workup was a near undetectable high-density lipoprotein (HDL)-cholesterol plasma level (0.09 mmol/L). Genetic analysis of key genes involved in HDL metabolism resulted in the discovery of 2 very rare mutations in the ABCA1 and APOA1 genes. We discuss the effects...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26073400
DOI: 10.1016/j.jacl.2015.01.006

Genes

ABCA1
APOA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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