Article
Altered biochemical properties of transient receptor potential vanilloid 6 calcium channel by peptide tags.
Biological & pharmaceutical bulletin - 1 Oct 2009
Park Eun-Jung, Kim Byung-Joo, Kim Su-Hwa, Kim Sung-Young, Sung Tae-Sik, Chae Hong-Gu, Kim Sang Jeong, Kim Jun, Park Hyun Ho, So Insuk, Jeon Ju-Hong
Abstract excerpt
Ion channels are commonly expressed in recombinant forms with peptide tags, which facilitates their molecular and electrophysiological studies. However, peptide tags may alter ion channel properties. Here we describe the differential effect of peptide tags on the biochemical properties of transient receptor potential vanilloid 6 (TRPV6) channels. Yellow fluorescent protein (YFP)-tagged wild-type TRPV6...
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