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Article

Roles for TRPV4 in disease: A discussion of possible mechanisms.

Cell calcium - 1 Dec 2024

Hernández-Vega Ana M, García-Villegas Refugio, Rosenbaum Tamara

Abstract excerpt

The transient receptor potential vanilloid 4 (TRPV4) ion channel is a ubiquitously expressed Ca2+-permeable ion channel that controls intracellular calcium ([Ca2+]i) homeostasis in various types of cells. The physiological roles for TRPV4 are tissue specific and the mechanisms behind this specificity remain mostly unclarified. It is noteworthy that mutations in the TRPV4 channel have been associated to a broad...

Topics

TRPV Cation Channels
Humans
Animals
Mutation
Calcium
Calcium Signaling
Disease

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 39609180
DOI: 10.1016/j.ceca.2024.102972

Genes

TRPV4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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