Article
TCF7L2 gene expression in human visceral and subcutaneous adipose tissue is differentially regulated but not associated with type 2 diabetes mellitus.
Metabolism: clinical and experimental - 1 Sept 2008
Kovacs Peter, Berndt Janin, Ruschke Karen, Klöting Nora, Schön Michael R, Körner Antje, Stumvoll Michael, Blüher Matthias
Abstract excerpt
Variants in the TCF7L2 gene have been associated with type 2 diabetes mellitus (T2DM), but the causal variant(s) is still unknown. We studied the TCF7L2 messenger RNA (mRNA) expression in paired samples of visceral and subcutaneous adipose tissue from 49 subjects using quantitative real-time polymerase chain reaction and its relation to obesity and T2DM. All subjects were genotyped for the previously described...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
