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Article

DNA topoisomerase II is a determinant of the tensile properties of yeast centromeric chromatin and the tension checkpoint.

Molecular biology of the cell - 1 Oct 2008

Warsi Tariq H, Navarro Michelle S, Bachant Jeff

Abstract excerpt

Centromeric (CEN) chromatin is placed under mechanical tension and stretches as kinetochores biorient on the mitotic spindle. This deformation could conceivably provide a readout of biorientation to error correction mechanisms that monitor kinetochore-spindle interactions, but whether CEN chromat...

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Identifiers

PMID: 18701701
DOI: 10.1091/mbc.e08-05-0547
PMCID: PMC2555933

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18701701-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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