Article
cato encodes a basic helix-loop-helix transcription factor implicated in the correct differentiation of Drosophila sense organs.
Developmental biology - 1 May 2000
Goulding S E, White N M, Jarman A P
Abstract excerpt
In Drosophila neurogenesis, proneural genes encode bHLH proteins that are required for neural precursor selection. But many vertebrate homologues are expressed later and are postulated to have multiple roles during neurogenesis. We have isolated a new Drosophila gene, cato, which encodes a protein with a bHLH domain that is closely related to that of the proneural protein Atonal. cato expression is restricted to...
Topics
- Amino Acid Sequence
- Animals
- Basic Helix-Loop-Helix Transcription Factors
- Cell Differentiation
- Cloning, Molecular
- DNA-Binding Proteins
- Drosophila
- Drosophila Proteins
- Gene Expression Regulation, Developmental
- Helix-Loop-Helix Motifs
- Immunohistochemistry
- Insect Proteins
- Microscopy, Electron, Scanning