Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

oto is a homeotic locus with a role in anteroposterior development that is partially redundant with Lim1.

Development (Cambridge, England) - 1 Nov 1999

Zoltewicz J S, Plummer N W, Lin M I, Peterson A S

Abstract excerpt

Genetic control of mammalian head development involves mechanisms that are shared with trunk development as well as mechanisms that are independent. For example, mutations in the nodal gene disrupt axis formation and head development while mutations in the Otx2 or Lim1 genes block head development without disrupting development of the trunk. We show here that the oto mutation on mouse chromosome 1 defines a locus...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Branchial Region
Share to Embryonic and Fetal Development

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Holoprosencephaly

Share to LIM-Homeodomain Proteins

Share to Pharynx

Share to Prosencephalon

Share to Telencephalon

Source

Identifiers

PMID: 10529425
DOI: 10.1242/dev.126.22.5085

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

oto is a homeotic locus with a role in anteroposterior development that is partially redundant with Lim1.PMID 10529425Read ↗

A targeted mouse Otx2 mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostral brain.Semantic proximity Read ↗

Complementary functions of Otx2 and Cripto in initial patterning of mouse epiblast.Semantic proximity Read ↗

Defective Neural Tube Closure and Anteroposterior Patterning in Mice Lacking the LIM Protein LMO4 or Its Interacting Partner Deaf-1Semantic proximity Read ↗

Deletion of OTX2 in neural ectoderm delays anterior pituitary development.Semantic proximity Read ↗

The role of Otx and Otp genes in brain development.Semantic proximity Read ↗

Zebrafish foxi one modulates cellular responses to Fgf signaling required for the integrity of ear and jaw patterning.Semantic proximity Read ↗

Otx1 function overlaps with Otx2 in development of mouse forebrain and midbrain.Semantic proximity Read ↗

Otx1 and Otx2 activities are required for the normal development of the mouse inner ear.Semantic proximity Read ↗

Mouse Otx2 functions in the formation and patterning of rostral head.Semantic proximity Read ↗

Chato, a KRAB zinc-finger protein, regulates convergent extension in the mouse embryo.Semantic proximity Read ↗

Requirement for Lmo4 in the vestibular morphogenesis of mouse inner ear.Semantic proximity Read ↗

Brother of cdo (umleitung) is cell-autonomously required for Hedgehog-mediated ventral CNS patterning in the zebrafish.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.