Article
Characteristics of HIV type 1 (HIV-1) glycoprotein 120 env sequences in mother-infant pairs infected with HIV-1 subtype CRF01_AE.
The Journal of infectious diseases - 15 Sept 2008
Samleerat Tanawan, Braibant Martine, Jourdain Gonzague, Moreau Alain, Ngo-Giang-Huong Nicole, Leechanachai Pranee, Hemvuttiphan Jittapol, Hinjiranandana Temsiri, Changchit Tikamporn, Warachit Boonyarat, Suraseranivong Veera, Lallemant Marc, Barin Francis
Abstract excerpt
We analyzed the characteristics of the envelope genes of human immunodeficiency virus type 1 in 17 mother-infant pairs infected with variants of the CRF01_AE clade. A total of 353 sequences covering almost the entire glycoprotein (gp) 120 region were available for analysis. We found that, even if the virus population in the mother was complex, only viruses of a restricted subset were transmitted to her infant,...
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