Article
HIV-1 genetic diversity and compartmentalization in mother/infant pairs infected with CRF01_AE.
AIDS (London, England) - 11 May 2007
Tovanabutra Sodsai, de Souza Mark, Sittisombut Nopporn, Sriplienchan Somchai, Ketsararat Vidhaya, Birx Deborah L, Khamboonrueng Chirasak, Nelson Kenrad E, McCutchan Francine E, Robb Merlin L
Abstract excerpt
Molecular characterization of C2-V5 envelope sequences from maternal plasma, peripheral blood mononuclear cells (PBMC), cervical secretions and infant PBMC was performed in eight CRF01_AE-infected mother/infant pairs. Maternal viruses were relatively homogeneous within a compartment but distinct in different compartments in mothers with high CD4 cell counts. Infant viruses were almost distinct, but...
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