Article
Identification of LTBP2 on chromosome 14q as a novel candidate gene for bone mineral density variation and fracture risk association.
The Journal of clinical endocrinology and metabolism - 1 Nov 2008
Cheung Ching-Lung, Sham Pak C, Chan Vivian, Paterson Andrew D, Luk Keith D K, Kung Annie W C
Abstract excerpt
CONTEXT: Low bone mineral density (BMD) is a major risk factor for osteoporotic fracture. Chromosome 14q has previously been linked to BMD variation in several genome-wide linkage scans in Caucasian populations. OBJECTIVE: Our objective was to replicate and identify the novel candidate genes in the quantitative trait loci (QTL) at chromosome 14q QTL. SUBJECTS AND METHODS: Eighteen microsatellite markers were...
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