Article
Association of paraoxonase gene cluster polymorphisms with ALS in France, Quebec, and Sweden.
Neurology - 12 Aug 2008
Valdmanis P N, Kabashi E, Dyck A, Hince P, Lee J, Dion P, D'Amour M, Souchon F, Bouchard J-P, Salachas F, Meininger V, Andersen P M, Camu W, Dupré N, Rouleau G A
Abstract excerpt
BACKGROUND: The paraoxonase gene cluster on chromosome 7 comprising the PON1-3 genes is an attractive candidate for association in amyotrophic lateral sclerosis (ALS) given the role of paraoxonase genes during the response to oxidative stress and their contribution to the enzymatic break down of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.