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Article

Cross-phenotype association tests uncover genes mediating nutrient response in Drosophila.

BMC genomics - 4 Nov 2016

Nelson Christopher S, Beck Jennifer N, Wilson Kenneth A, Pilcher Elijah R, Kapahi Pankaj, Brem Rachel B

Abstract excerpt

BACKGROUND: Obesity-related diseases are major contributors to morbidity and mortality in the developed world. Molecular diagnostics and targets of therapies to combat nutritional imbalance are urgently needed in the clinic. Invertebrate animals have been a cornerstone of basic research efforts to dissect the genetics of metabolism and nutrient response. We set out to use fruit flies reared on restricted and...

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Identifiers

PMID: 27809764
DOI: 10.1186/s12864-016-3137-9
PMCID: PMC5095962

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