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Article

A conserved role for syndecan family members in the regulation of whole-body energy metabolism.

PloS one - 23 Jun 2010

De Luca Maria, Klimentidis Yann C, Casazza Krista, Chambers Michelle Moses, Cho Ruth, Harbison Susan T, Jumbo-Lucioni Patricia, Zhang Shaoyan, Leips Jeff, Fernandez Jose R

Abstract excerpt

Syndecans are a family of type-I transmembrane proteins that are involved in cell-matrix adhesion, migration, neuronal development, and inflammation. Previous quantitative genetic studies pinpointed Drosophila Syndecan (dSdc) as a positional candidate gene affecting variation in fat storage between two Drosophila melanogaster strains. Here, we first used quantitative complementation tests with dSdc mutants to...

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Identifiers

PMID: 20585652
DOI: 10.1371/journal.pone.0011286
PMCID: PMC2890571

Genes

PGC
SDC4

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