Article
Association of the Laminin, Alpha 5 (LAMA5) rs4925386 with height and longevity in an elderly population from Southern Italy.
Mechanisms of ageing and development - 1 Apr 2016
De Luca Maria, Crocco Paolina, De Rango Francesco, Passarino Giuseppe, Rose Giuseppina
Abstract excerpt
Studies in animal models and humans suggest that reduced growth and adult stature are associated with lifespan extension. Moreover, epidemiological studies reported a positive association between adult height and risk of multiple cancers. Yet, it is unclear which factors mediate these relationships. Laminins are major components of the basement membranes and cooperate with growth factors and matrix-dependent...
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