Article

Human genetic studies and zebrafish models identify Plxna4 as a regulator of adiposity, somatic growth, and feeding behaviours

2025-03-16

Abstract excerpt

Obesity is a major public health crisis, affecting billions worldwide and increasing the risk of metabolic and cardiovascular diseases. While lifestyle factors play a role, genetic variation is a key determinant of both obesity susceptibility and the efficacy of treatment strategies. Recent studies have implicated the Semaphorin 3 signalling pathway in obesity; however, specific roles for pathway components remain...

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Literature Corpus work: 859162b2-d07b-5f55-b048-0fffe28dabfc
DOI: 10.1101/2025.03.15.643290

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