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Article

Quercetin-mediated longevity in Caenorhabditis elegans: is DAF-16 involved?

Mechanisms of ageing and development - 1 Oct 2008

Saul Nadine, Pietsch Kerstin, Menzel Ralph, Steinberg Christian E W

Abstract excerpt

The polyphenol quercetin has recently been found to extend lifespan and increase stress resistance in the nematode Caenorhabditis elegans. The forkhead transcription factor DAF-16 has previously been linked to these effects. However, by using a daf-16(mgDf50) mutant strain, we show that quercetin exposure leads to increased mean lifespans up to 15%. Furthermore, quercetin-treated daf-16(mgDf50) worms show an...

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Identifiers

PMID: 18692520
DOI: 10.1016/j.mad.2008.07.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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