Article
Quercetin mediated lifespan extension in Caenorhabditis elegans is modulated by age-1, daf-2, sek-1 and unc-43.
Biogerontology - 1 Oct 2009
Pietsch Kerstin, Saul Nadine, Menzel Ralph, Stürzenbaum Stephen R, Steinberg Christian E W
Abstract excerpt
The nematode Caenorhabditis elegans responds to flavonoid-rich diets with improved health and longevity. The precise mechanism(s) responsible for this remains to be identified, but is believed to be linked to the highly antioxidative properties of flavonoids. This study provides a dissection of lifespan modulation by the flavonoid quercetin. In detail, quercetin was shown not to act as a simple antimicrobial...
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