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Article

Human leukocyte antigen class I genotypes in relation to heterosexual HIV type 1 transmission within discordant couples.

Journal of immunology (Baltimore, Md. : 1950) - 15 Aug 2008

Tang Jianming, Shao Wenshuo, Yoo Yun Joo, Brill Ilene, Mulenga Joseph, Allen Susan, Hunter Eric, Kaslow Richard A

Abstract excerpt

Differences in immune control of HIV-1 infection are often attributable to the highly variable HLA class I molecules that present viral epitopes to CTL. In our immunogenetic analyses of 429 HIV-1 discordant Zambian couples (infected index partners paired with cohabiting seronegative partners), several HLA class I variants in index partners were associated with contrasting rates and incidence of HIV-1 transmission...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18684953
DOI: 10.4049/jimmunol.181.4.2626
PMCID: PMC2570252

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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