Article
Alix differs from ESCRT proteins in the control of autophagy.
Biochemical and biophysical research communications - 10 Oct 2008
Petiot Anne, Strappazzon Flavie, Chatellard-Causse Christine, Blot Béatrice, Torch Sakina, Verna Jean-Marc, Sadoul Rémy
Abstract excerpt
Alix/AIP1 is a cytosolic protein that regulates cell death through mechanisms that remain unclear. Alix binds to two protein members of the so-called Endosomal Sorting Complex Required for Transport (ESCRT), which facilitates membrane fission events during multivesicular endosome formation, enveloped virus budding and cytokinesis. Alix itself has been suggested to participate in these cellular events and is thus...
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