Article
Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins
30 Sept 2003
Abstract excerpt
The release of enveloped viruses from infected cells often requires a virally encoded activity, termed a late-budding domain (L domain), encoded by essential PTAP, PPXY, or YPDL sequence motifs. PTAP-type L domains recruit one of three endosomal sorting complexes required for transport (ESCRT-I). However, subsequent events in viral budding are poorly defined, and neither YPDL nor PPXY-type L domains require...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
