Article
DdAlix, an Alix/AIP1 homolog in Dictyostelium discoideum, is required for multicellular development under low Ca2+ conditions.
Gene - 4 Aug 2004
Ohkouchi Susumu, El-Halawany Medhat S, Aruga Fumika, Shibata Hideki, Hitomi Kiyotaka, Maki Masatoshi
Abstract excerpt
Apoptosis-linked gene 2 (ALG-2) interacting protein X (Alix), also called AIP1, is a widely conserved protein in eukaryotes. Alix and its homologs are involved in various phenomena such as apoptosis, regulation of cell adhesion, protein sorting, adaptation to stress conditions, and budding of human immunodeficiency virus (HIV). To investigate the role of Alix in development, we identified an Alix homolog in the...
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