Article
Increased susceptibility to collagen-induced arthritis in female mice carrying congenic Cia40/Pregq2 fragments.
Arthritis research & therapy - 1 Jan 2008
Liljander Maria, Andersson Asa, Holmdahl Rikard, Mattsson Ragnar
Abstract excerpt
INTRODUCTION: Collagen-induced arthritis (CIA) in mice is a commonly used experimental model for rheumatoid arthritis (RA). We have previously identified a significant quantitative trait locus denoted Cia40 on chromosome 11 that affects CIA in older female mice. This locus colocalizes with another locus, denoted Pregq2, known to affect reproductive success. The present study was performed to evaluate the role of...
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