Article
AXIN2 and CDH1 polymorphisms, tooth agenesis, and oral clefts.
Birth defects research. Part A, Clinical and molecular teratology - 1 Feb 2009
Letra Ariadne, Menezes Renato, Granjeiro Jose M, Vieira Alexandre R
Abstract excerpt
BACKGROUND: AXIN2 and CDH1 genes play important roles during craniofacial morphogenesis. Mutations in these genes have been described in families presenting colorectal cancer and tooth agenesis, and gastric cancer and cleft lip/palate (CL/P). Oral clefts have been associated with tooth agenesis. We investigated if AXIN2 and CDH1 polymorphisms were associated with clefts or with any associated dental...
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