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Article

Functional analysis of a novel missense mutation in AXIN2 associated with non-syndromic tooth agenesis.

European journal of oral sciences - 1 Jun 2016

Yue Haitang, Liang Jia, Yang Kai, Hua Bo, Bian Zhuan

Abstract excerpt

Tooth agenesis is a congenital anomaly frequently seen in humans. Several genes have been associated with non-syndromic tooth agenesis, including msh homeobox 1 (MSX1), paired box 9 (PAX9), axis inhibition protein 2 (AXIN2), ectodysplasin A (EDA), and wingless-type MMTV integration site family member 10A (WNT10A). In this study, we investigated a Chinese family with non-syndromic tooth agenesis. A novel missense...

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Source

Identifiers

PMID: 27090353
DOI: 10.1111/eos.12273

Genes

AXIN2
EDA
MSX1
PAX9

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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