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Article

Grainyhead genes and mammalian neural tube closure.

Birth defects research. Part A, Clinical and molecular teratology - 1 Oct 2008

Gustavsson Peter, Copp Andrew J, Greene Nicholas D E

Abstract excerpt

BACKGROUND: Grainyhead genes encode a family of transcription factors that are well conserved from fly to human. The three mammalian homologues, Grainyhead-like-1, -2, and -3 are expressed in various ectodermal and endodermal cell types during embryonic development and in adult skin. Gene targeting in mice has demonstrated functional roles for Grhl1 and Grhl3 in epidermal integrity and wound healing ability of...

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Identifiers

PMID: 18683893
DOI: 10.1002/bdra.20494

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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