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Article

Polymorphism of detoxification genes and cell resistance to mutagens in patients with Ehlers-Danlos syndrome.

Bulletin of experimental biology and medicine - 1 Nov 2007

Kuz'mina N S, Shipaeva E V, Semyachkina A N, Vasil'eva I M, Kovalenko L P, Durnev A D, Zasukhina G D

Abstract excerpt

Study of polymorphism in 3 genes of the glutathione S-transferase family (GSTM1, GSTT1, and GSTP1) in children with Ehlers-Danlos syndrome whose cells were defective in repair of gamma-induced DNA damages revealed accumulation of GSTM1(+) genotypes compared to children of the control group. Generation of reactive oxygen species by neutrophils from patients with this syndrome was higher than in healthy donors. Our...

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Source

Identifiers

PMID: 18683505
DOI: 10.1007/s10517-007-0414-2

Genes

GSTM1
GSTP1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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