Article
[The effect of polymorphism of genes of xenobiotics detoxication on the frequencies of spontaneous and induced chromosome aberrations in human lymphocytes].
Radiatsionnaia biologiia, radioecologiia - 1 Jan 2000
Sal'nikova L E, Akaeva E A, Elisova T V, Kuznetsova G I, Kuz'mina N S, Vesnina I N, Lapteva N Sh, Chumachenko A G, Romanchuk V A, Rubanovich A V
Abstract excerpt
Here presented the data on the frequencies of chromosome aberrations in lymphocytes of peripheral blood of 97 volunteers depending on genotypes by genes of xenobiotics detoxication before and after gamma-irradiation with dose of 1 Gy in vitro. The frequencies of aberrations were estimated by analyzing not less than 500-1000 metaphases per person. The data of cytogenetic analysis were compared with the results of...
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