Article
High-throughput isolation and mapping of C. elegans mutants susceptible to pathogen infection.
PloS one - 6 Aug 2008
Fuhrman Laura E, Shianna Kevin V, Aballay Alejandro
Abstract excerpt
We present a novel strategy that uses high-throughput methods of isolating and mapping C. elegans mutants susceptible to pathogen infection. We show that C. elegans mutants that exhibit an enhanced pathogen accumulation (epa) phenotype can be rapidly identified and isolated using a sorting system that allows automation of the analysis, sorting, and dispensing of C. elegans by measuring fluorescent bacteria inside...
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