Article
Associations of Toll-like receptor 7 and 8 Polymorphisms with Asthma and Asthma-related Phenotypes in a Chinese Han Population.
Iranian journal of allergy, asthma, and immunology - 1 Dec 2015
Zhang Qian, Qian Fen-Hong, Yin Xiao-Wei, Cao Qi, Bai Jian-Ling, Du Qiang, Shi Yi
Abstract excerpt
Toll-like receptor (TLR) 7 and 8 mediate anti-virus immunity and are of particular relevance to asthma. However, very little information about genetic association on TLR7/8 and asthma are available. This study aimed to evaluate the effects of polymorphisms in TLR7 and 8 on asthma risk and asthma-related phenotypes in a Chinese Han population. We enrolled 462 unrelated adult asthmatic patients and 398 healthy...
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