Article
Association between polymorphisms in the apolipoprotein D gene and sporadic Alzheimer's disease.
Brain research - 3 Oct 2008
Chen Yan, Jia Longfei, Wei Cuibai, Wang Fen, Lv Haiyan, Jia Jianping
Abstract excerpt
Apolipoprotein D (apoD) is a lipoprotein-associated glycoprotein that is increased in the hippocampus and cerebrospinal fluid of patients with Alzheimer's disease (AD), which implies that apoD might be involved in the pathogenesis of AD. We used polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and DNA sequencing techniques to screen all exons (1-5) and the flanking exon-intron...
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