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Article

Genetic association between APOA1 and APOD polymorphisms and Alzheimer's disease in a Japanese population.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Nov 2013

Shibata Nobuto, Nagata Tomoyuki, Shinagawa Shunichiro, Ohnuma Tohru, Shimazaki Hiromi, Komatsu Miwa, Kuerban Bolati, Tomson Katrin, Nakayama Kazuhiko, Yamada Hisashi, Arai Heii

Abstract excerpt

Alterations in lipoproteins are involved in the pathophysiology of Alzheimer's disease (AD). For sporadic AD, the Apolipoprotein E (APOE) is recognized as a sole genetic risk factor. Apolipoprotein A1 (APOA1) has been suggested to bind amyloid β and promoter polymorphisms of the APOA1 gene were likely to affect the onset of the disease. Apolipoprotein D (APOD) expression is upregulating in AD brain and evidences...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 23690001
DOI: 10.1007/s00702-013-1036-7

Genes

APOD
APOA1
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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