Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of fibroblast growth factor receptor 2 in kidney mesenchyme.

Pediatric research - 1 Dec 2008

Hains David, Sims-Lucas Sunder, Kish Kayle, Saha Monalee, McHugh Kirk, Bates Carlton M

Abstract excerpt

Conditional deletion of murine fibroblast growth factor receptors (Fgfrs) 1 and 2 in metanephric mesenchyme leads to renal agenesis with unbranched ureteric buds; however, there are occasionally two buds per nephric duct. Our goal was to determine whether conditional deletion of Fgfr1 or Fgfr2 alone resulted in multiple ureteric bud induction sites. Although deletion of Fgfr1 alone results in no abnormalities,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Morphogenetic Protein 4
Share to Glial Cell Line-Derived Neurotrophic Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mesoderm

Share to Phosphoproteins

Share to Receptor, Fibroblast Growth Factor, Type 1

Share to Receptor, Fibroblast Growth Factor, Type 2

Share to Receptors, Immunologic

Share to Ureter

Source

Open in PubMed Open full text

Identifiers

PMID: 18670373
DOI: 10.1203/PDR.0b013e318187cc12
PMCID: PMC2647852

Genes

GDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of fibroblast growth factor receptor 2 in kidney mesenchyme.PMID 18670373Read ↗

Fibroblast growth factor receptor signaling in kidney and lower urinary tract development.Semantic proximity Read ↗

Deletion of Fibroblast Growth Factor Receptor 2 from the Peri-Wolffian Duct Stroma Leads to Ureteric Induction Abnormalities and Vesicoureteral RefluxSemantic proximity Read ↗

Ureteric Morphogenesis Requires Fgfr1 and Fgfr2/Frs2α Signaling in the Metanephric MesenchymeSemantic proximity Read ↗

Deletion of Frs2alpha from the ureteric epithelium causes renal hypoplasia.Semantic proximity Read ↗

Three-Dimensional Imaging Reveals Ureteric and Mesenchymal Defects in Fgfr2-Mutant KidneysSemantic proximity Read ↗

Independent roles of Fgfr2 and Frs2α in ureteric epitheliumSemantic proximity Read ↗

Non-canonical Wnt5a/Ror2 signaling regulates kidney morphogenesis by controlling intermediate mesoderm extensionSemantic proximity Read ↗

High incidence of vesicoureteral reflux in mice with Fgfr2 deletion in kidney mesenchyma.Semantic proximity Read ↗

Essential role of stromal mesenchyme in kidney morphogenesis revealed by targeted disruption of Winged Helix transcription factor BF-2.Semantic proximity Read ↗

Minimal phenotype of mice homozygous for a null mutation in the forkhead/winged helix gene, Mf2.Semantic proximity Read ↗

Fgfr2 is integral for bladder mesenchyme patterning and function.Semantic proximity Read ↗

Fgfr2 is integral for bladder mesenchyme patterning and function.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.