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Article

Fibroblast growth factor receptor signaling in kidney and lower urinary tract development.

Pediatric nephrology (Berlin, Germany) - 1 Jun 2016

Walker Kenneth A, Sims-Lucas Sunder, Bates Carlton M

Abstract excerpt

Fibroblast growth factor receptors (FGFRs) and FGF ligands are highly expressed in the developing kidney and lower urinary tract. Several classic studies showed many effects of exogenous FGF ligands on embryonic renal tissues in vitro and in vivo. Another older landmark publication showed that mice with a dominant negative Fgfr fragment had severe renal dysplasia. Together, these studies revealed the importance...

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Identifiers

PMID: 26293980
DOI: 10.1007/s00467-015-3151-1
PMCID: PMC4761523

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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