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Article

Fgfr2 is integral for bladder mesenchyme patterning and function.

American journal of physiology. Renal physiology - 15 Apr 2015

Walker K A, Ikeda Y, Zabbarova I, Schaefer C M, Bushnell D, De Groat W C, Kanai A, Bates C M

Abstract excerpt

While urothelial signals, including sonic hedgehog (Shh), drive bladder mesenchyme differentiation, it is unclear which pathways within the mesenchyme are critical for its development. Studies have shown that fibroblast growth factor receptor (Fgfr)2 is necessary for kidney and ureter mesenchymal development. The objective of the present study was to determine the role of Fgfr2 in the bladder mesenchyme. We used...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptor, Fibroblast Growth Factor, Type 2

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Source

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Identifiers

PMID: 25656370
DOI: 10.1152/ajprenal.00624.2014
PMCID: PMC4398839

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