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Article

Association study of a polymorphism in clock gene PERIOD3 and risk of inflammatory bowel disease.

Chronobiology international - 1 Oct 2012

Mazzoccoli Gianluigi, Palmieri Orazio, Corritore Giuseppe, Latiano Tiziana, Bossa Fabrizio, Scimeca Daniela, Biscaglia Giuseppe, Valvano Maria Rosa, D'Incà Renata, Cucchiara Salvatore, Stronati Laura, Annese Vito, Andriulli Angelo, Latiano Anna

Abstract excerpt

Altered body rhythmicity and deregulated clock gene expression may cause circadian disruption, which can lead to immune dysregulation and chronic inflammatory diseases. PERIOD3 (PER3) polymorphisms have been associated with circadian disruption and changed secretion of cytokines involved in chronic inflammation. Crohn's disease (CD) and ulcerative colitis (UC) are multifactorial diseases resulting from complex...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22881285
DOI: 10.3109/07420528.2012.705935

Genes

PER3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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