Article
NLRP3 gene is associated with ulcerative colitis (UC), but not Crohn's disease (CD), in Chinese Han population.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] - 1 Dec 2014
Zhang Hong-xin, Wang Zheng-ting, Lu Xiong-xiong, Wang Yan-gui, Zhong Jie, Liu Jie
Abstract excerpt
OBJECTIVE: This study aimed to investigate whether NLRP3 is associated with IBD in Chinese Han population. METHODS: Three SNPs were genotyped using polymerase chain reaction with sequence-specific primers in 288 patients [232 Crohn's disease (CD) patients, 56 ulcerative colitis (UC) patients] and 274 controls. RESULTS: In IBD group, the results showed no significant association. When subdivided to CD and UC, it...
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