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Article

Gene-Environment Interactions for Parkinson's Disease.

Annals of neurology - 1 Apr 2024

Reynoso Alexandra, Torricelli Roberta, Jacobs Benjamin Meir, Shi Jingchunzi, Aslibekyan Stella, Norcliffe-Kaufmann Lucy, Noyce Alastair J, Heilbron Karl

Abstract excerpt

OBJECTIVE: Parkinson's disease (PD) is a neurodegenerative disorder with complex etiology. Multiple genetic and environmental factors have been associated with PD, but most PD risk remains unexplained. The aim of this study was to test for statistical interactions between PD-related genetic and environmental exposures in the 23andMe, Inc. research dataset. METHODS: Using a validated PD polygenic risk score and...

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Source

Identifiers

PMID: 38113326
DOI: 10.1002/ana.26852

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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