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Article

A locus on distal chromosome 11 (ahl8) and its interaction with Cdh23 ahl underlie the early onset, age-related hearing loss of DBA/2J mice.

Genomics - 1 Oct 2008

Johnson Kenneth R, Longo-Guess Chantal, Gagnon Leona H, Yu Heping, Zheng Qing Yin

Abstract excerpt

The DBA/2J inbred strain of mice is used extensively in hearing research, yet little is known about the genetic basis for its early onset, progressive hearing loss. To map underlying genetic factors we analyzed recombinant inbred strains and linkage backcrosses. Analysis of 213 mice from 31 BXD recombinant inbred strains detected linkage of auditory brain-stem response thresholds with a locus on distal chromosome...

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Identifiers

PMID: 18662770
DOI: 10.1016/j.ygeno.2008.06.007
PMCID: PMC2836023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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