Article
An Age-Related Hearing Protection Locus on Chromosome 16 of BXD Strain Mice.
Neural plasticity - 1 Jan 2020
Zheng Qing Yin, Kui Lihong, Xu Fuyi, Zheng Tihua, Li Bo, McCarty Melinda, Sun Zehua, Zhang Aizheng, Liu Luying, Starlard-Davenport Athena, Stepanyan Ruben, Hu Bo Hua, Lu Lu
Abstract excerpt
Inbred mouse models are widely used to study age-related hearing loss (AHL). Many genes associated with AHL have been mapped in a variety of strains. However, little is known about gene variants that have the converse function-protective genes that confer strong resistance to hearing loss. Previously, we reported that C57BL/6J (B6) and DBA/2J (D2) strains share a common hearing loss allele in Cdh23. The cadherin...
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