Article
Genetic basis for susceptibility to noise-induced hearing loss in mice.
Hearing research - 1 May 2001
Davis R R, Newlander J K, Ling X, Cortopassi G A, Krieg E F, Erway L C
Abstract excerpt
The C57BL/6J (B6) and DBA/2J (D2) inbred strains of mice exhibit an age-related hearing loss (AHL) due to a recessive gene (Ahl) that maps to Chromosome 10. The Ahl gene is also implicated in the susceptibility to noise-induced hearing loss (NIHL). The B6 mice (Ahl/Ahl) are more susceptible to NIHL than the CBA/CaJ (CB) mice (+(Ahl)). The B6xD2.F(1) hybrid mice (Ahl/Ahl) are more susceptible to NIHL than the...
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