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Article

Genetic dissection of susceptibility to audiogenic seizures in inbred mice.

Proceedings of the National Academy of Sciences of the United States of America - 15 Jun 1991

Neumann P E, Collins R L

Abstract excerpt

Mice of some inbred strains, such as 21-day-old DBA/2J mice, have generalized convulsions when exposed to intense auditory stimulation. Analysis of susceptibility to audiogenic seizures in BXD recombinant inbred strains has demonstrated the influence of at least three loci. One locus, Asp-1, is located on chromosome 12 between Ah and D12Nyu1; another locus, Asp-2, is on chromosome 4, tightly linked to b. Here we...

Topics

Animals
Chromosomes
Genetic Predisposition to Disease
Mice
Phenotype
Seizures

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2052619
DOI: 10.1073/pnas.88.12.5408
PMCID: PMC51882

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2052619-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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