Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Age-related hearing loss and the ahl locus in mice.

Hearing research - 1 Feb 2004

Keithley Elizabeth M, Canto Cecilia, Zheng Qing Yin, Fischel-Ghodsian Nathan, Johnson Kenneth R

Abstract excerpt

C57BL/6 (B6) mice experience hearing loss and cochlear degeneration beginning about mid-life, whereas CAST/Ei (CAST) mice retain normal hearing until old age. A locus contributing to the hearing loss of B6 mice, named age-related hearing loss (ahl), was mapped to Chromosome 10. A homozygous, congenic strain of mice (B6.CAST-+ahl ), generated by crossing B6 (ahl/ahl) and CAST (+ahl/+ahl) mice has the same genomic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Analysis of Variance
Share to Auditory Threshold

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cochlea

Share to Evoked Potentials, Auditory, Brain Stem

Share to Homozygote

Share to Organ of Corti

Share to Presbycusis

Source

Open in PubMed Open full text

Identifiers

PMID: 14759567
DOI: 10.1016/S0378-5955(03)00365-4
PMCID: PMC2858220

Genes

CAST

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Age-related hearing loss and the ahl locus in mice.PMID 14759567Read ↗

A major gene affecting age-related hearing loss in C57BL/6J mice.Semantic proximity Read ↗

A major gene affecting age-related hearing loss is common to at least ten inbred strains of mice.Semantic proximity Read ↗

The effect of an age-related hearing loss gene (Ahl) on noise-induced hearing loss and cochlear damage from low-frequency noise.Semantic proximity Read ↗

Ahl2, a second locus affecting age-related hearing loss in mice.Semantic proximity Read ↗

Genetic basis for susceptibility to noise-induced hearing loss in mice.Semantic proximity Read ↗

Fine mapping of Ahl3 affecting both age-related and noise-induced hearing loss.Semantic proximity Read ↗

Genetics of age-related hearing loss in mice. III. Susceptibility of inbred and F1 hybrid strains to noise-induced hearing loss.Semantic proximity Read ↗

A locus on distal chromosome 11 (ahl8) and its interaction with Cdh23 ahl underlie the early onset, age-related hearing loss of DBA/2J mice.Semantic proximity Read ↗

Hearing loss associated with the modifier of deaf waddler (mdfw) locus corresponds with age-related hearing loss in 12 inbred strains of mice.Semantic proximity Read ↗

Genetics of age-related hearing loss in mice. IV. Cochlear pathology and hearing loss in 25 BXD recombinant inbred mouse strains.Semantic proximity Read ↗

Genome-wide association study for age-related hearing loss in CFW miceSemantic proximity Read ↗

Evaluating cochlear function and the effects of noise exposure in the B6.CAST+Ahl mouse with distortion product otoacoustic emissions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.