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Article

Methylation status in healthy subjects with normal and high serum folate concentration.

Nutrition (Burbank, Los Angeles County, Calif.) - 1 Jan 2000

Hirsch Sandra, Ronco Ana María, Guerrero-Bosagna Carlos, de la Maza María Pía, Leiva Laura, Barrera Gladys, Llanos Miguel, Alliende M Angelica, Silva Francisca, Bunout Daniel

Abstract excerpt

OBJECTIVE: We assessed the impact of high serum folate concentration on erythrocyte S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH) concentrations, SAM/SAH ratio, CpG methylation levels across the promoter region of the extracellular superoxide dismutase (ec-SOD) gene, and ec-SOD activity in healthy men. METHODS: Serum folate levels were measured in 111 subjects who were categorized in quintiles...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

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Source

Identifiers

PMID: 18653314
DOI: 10.1016/j.nut.2008.05.018

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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