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Article

ras gene mutations are absent in NMU-induced mammary carcinomas from aging rats.

Carcinogenesis - 1 Oct 2000

Thompson T A, Haag J D, Gould M N

Abstract excerpt

Carcinoma induction in the rat mammary carcinogenesis model is age dependent. In this study, mammary cancer susceptibility and ras gene activation were investigated in rats exposed to N:-methyl-N:-nitrosourea (NMU) at 2, 6, 8 and 15 months. Animals were resistant to NMU-induced mammary tumor development when exposed at 6 and 8 months of age, whereas a significant number of mammary carcinomas developed in animals...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

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Share to Mammary Neoplasms, Experimental

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Source

Identifiers

PMID: 11023551
DOI: 10.1093/carcin/21.10.1917

Genes

NMU

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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