Article
Molecular analysis of the KIT gene in gastrointestinal stromal tumors with novel mutations.
Applied immunohistochemistry & molecular morphology : AIMM - 1 Jan 2014
Calibasi Gizem, Baskin Yasemin, Alyuruk Hakan, Cavas Levent, Oztop Ilhan, Sagol Ozgul, Atila Koray, Ellidokuz Hulya, Yilmaz Ugur
Abstract excerpt
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. KIT gene mutations have great importance for GISTs. This study evaluated the relationship between KIT mutations and GIST clinicopathologic features to define region-specific and population-specific differences. Genomic DNA was extracted from 60 GISTs, and polymerase chain reaction was performed for KIT...
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