Article
Hedgehog-Patched pathway aberrations in a malignant triton tumor case study.
Oncology reports - 1 Aug 2008
Bura Miljenko, Musani Vesna, Cretnik Maja, Botica Iva, Levanat Sonja
Abstract excerpt
Transition from malignant schwannoma to malignant triton tumor is analyzed in a case report on a patient with recurring cancers and suspected familial predisposition. It is hypothesized that rhabdomyoblastic differentiation, which distinguishes triton from schwannoma, might be attributable to Hedgehog-Patched pathway malfunctioning. Loss of one Patched gene allele was found in the tissue of advanced triton, but...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
