Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hedgehog Signaling Pathway as Genetic and Epigenetic Target in Ovarian Tumors.

Current pharmaceutical design - 1 Jan 2017

Levanat Sonja, Sabol Maja, Musani Vesna, Ozretic Petar, Trnski Diana

Abstract excerpt

BACKGROUND: Hedgehog signaling pathway is a developmental pathway mostly inactive in adult tissues, with the exception of stem cells. It is often found upregulated in various tumors, and associated with cancer stem cell maintenance. METHODS: This review focuses on different aspects of Hedgehog activation in tumors, with special emphasis on ovarian tumors and their treatment. RESULTS: Mutations in pathway...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents
Share to Epigenesis, Genetic
Share to Hedgehog Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Ovarian Neoplasms

Share to Signal Transduction

Source

Identifiers

PMID: 27719639
DOI: 10.2174/1381612822666161006154705

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hedgehog Signaling Pathway as Genetic and Epigenetic Target in Ovarian Tumors.PMID 27719639Read ↗

[Hedgehog signaling pathway and its impact on development of cancer therapy].Semantic proximity Read ↗

Hedgehog signaling: modulation of cancer properies and tumor mircroenvironmentSemantic proximity Read ↗

The Utility of Hedgehog Signaling Pathway Inhibition for CancerSemantic proximity Read ↗

Hedgehog pathway and cancer: A new area (Review).Semantic proximity Read ↗

Targeting embryonic signaling pathways in cancer therapySemantic proximity Read ↗

Hedgehog signaling in cancer stem cells: a focus on hematological cancersSemantic proximity Read ↗

Hedgehog Signaling: Networking to Nurture a Promalignant Tumor MicroenvironmentSemantic proximity Read ↗

Hedgehog-GLI pathway in medulloblastoma.Semantic proximity Read ↗

Misactivation of Hedgehog signaling causes inherited and sporadic cancersSemantic proximity Read ↗

Hedgehog signaling pathway in colorectal cancer: function, mechanism, and therapySemantic proximity Read ↗

Activation of the hedgehog-signaling pathway in human cancer and the clinical implicationsSemantic proximity Read ↗

Pathways and consequences: Hedgehog signaling in human diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.