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Article

The Hedgehog signalling pathway and cancer.

The Journal of pathology - 1 Apr 2001

Saldanha G

Abstract excerpt

The Hedgehog signalling pathway is important in embryological development and is highly conserved through evolution. Recently Patched, a member of the pathway, was found to be important in Gorlin's syndrome. Inherited Patched gene mutations underlie the syndrome, in which a key feature is multiple basal cell carcinomas (BCCs). The gene is also mutated in sporadic BCCs as well as in sporadic occurrences of other...

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Identifiers

PMID: 11276000
DOI: 10.1002/1096-9896(2000)9999:9999<::AID-PATH815>3.0.CO;2-N

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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